In the field of drug packaging for syringe injection, so far, all prefilled syringes in the US market are made of glass. The new plastic substitutes will quickly replace this packaging for a wider range of disinfection products. The excellent barrier properties of the glass make it ideal for packaging. The industry has always believed that the glass for the injection of drugs than the plastic low response, and the use of glass, the amount of precipitation and extraction is also lower. However, for some products, this concept has changed. Some new drugs are not compatible with glass. Glass may contain free alkaline oxides and trace metals. For products with higher pH, the glass leaches alkaline components, resulting in incompatible or glass delamination problems. All major packaging will contain ingredients such as raw materials, impurities, contaminants and decomposition products, which may accumulate in the product. These ingredients are often referred to as precipitates and extracts and remain stable when stored in a package that is required for use. At the same time, the safety of the packaging components must be assessed to determine whether they will be hazardous to the patient during the period of use and product life. Including compounds that are dissolved in the packaging surface of the product.

   All glass syringes and various types of plastic have different precipitates and extracts. The problem, however, is that the specific product is more sensitive to which precipitates and extracts, and the potential interactions between packaging and products are gaining increasing attention because of the increasing use of proteins and peptides in the treatment The At present, trace metals, antioxidants, stabilizers or contaminants or process contaminants from the packaging process present in the product can affect product stability. In the event of replacement of the supplier, a wide range of stability studies must be conducted to confirm that the intended plastic composition of the supplier is compatible with the user's product. In addition, it should also be considered that if the plastic resin manufacturing process changes, or replace some of the raw material suppliers, may need to spend a lot of time and work in the new variables on the identification of qualified. The protein has a very complex nature. Experience tells us that protein can react with the vast majority of substances. At this point, the protein will change the original nature, the formation of particles, showing the gel state, like eggs, like coagulation. At present, there are a number of large glass suppliers to meet the requirements of the USP I type of glass, successfully resolved the long-term availability of components. USP I-type standardized glass, even if it is recognized by the market, may also be due to the replacement of suppliers and bring new problems. For the plastic packaging also has the same problem, most of the injection of pharmaceutical packaging used in the use of plastic are listed standards.

  Taizhou thousands of Johnson Plastic Co., Ltd. is a commitment to the medical aspects of research and development, production and sales as one of the modern enterprise! The company mainly engaged in: pet chip syringes, medical silicone O-ring, medical medical plastic products!